How sensory signals are detected: Structure function relationships in peripheral sensory nerve terminals

Project Details

Peripherally located small diameter sensory nerve terminals are critical for coding pain and changes in temperature, but our current lack of understanding of how they work limits our ability to target specific therapies associated with these sensory modalities. This study uses a combination of electrophysiological recording, neuroanatomical tracing, immunohistochemistry and high resolution confocal microscopy to provide new insights into how sensory signals are transformed into action potentials in sensory nerve terminals that code for pain and changes in temperature.

Researchers

Jenny Thai, Research assistant
Sara Nencini, PhD student
Abdulhakeem Alamri, PhD student

Collaborators

Associate Professor James Brock
Dr Michael Barrington
Associate Professor Louise Purton

Research Group

Ivanusic laboratory: Pain and sensory mechanisms



Faculty Research Themes

Neuroscience

School Research Themes

Biomedical Neuroscience, Molecular Mechanisms of Disease, Systems Biology, Therapeutics & Translation



Key Contact

For further information about this research, please contact the research group leader.

Department / Centre

Anatomy and Neuroscience

Unit / Centre

Ivanusic laboratory: Pain and sensory mechanisms