Cell biology of membrane receptors regulating the serum half-life of therapeutic proteins

Project Details

The neonatal Fc receptor (FcR) plays a critical role in regulating the half-live of a range of serum proteins, including IgG, in the adult. Our research, in collaboration with CSL, is investigating the membrane recycling pathway of the neonatal Fc receptor, information which is critical for the optimizing the life span of therapeutic proteins.

Research Group

Gleeson laboratory: Membrane trafficking and protein sorting in health and disease and development of new therapeutics

Faculty Research Themes

Infection and Immunology

School Research Themes

Infection & Immunity, Therapeutics & Translation, Cell Signalling

Key Contact

For further information about this research, please contact the research group leader.

Department / Centre

Biochemistry and Molecular Biology