Therapeutics & Translation

The translation of discoveries in Biomedical Sciences across to clinical and commercial settings is a feature of many of the research activities in the School

Groups / Projects Research Lead Dept / Centre
A universal vaccine against influenza A Professor David Jackson Microbiology and Immunology
Aminoacyl-tRNA synthetases enzymes as drug targets Dr Stuart Ralph Biochemistry and Molecular Biology
Ascher laboratory: Structural biology and bioinformatics Dr David Ascher
Biochemistry and Molecular Biology
Australian bite and sting trends: Australian Venomous Injury Project (AVIP) Dr Ronelle Welton Pharmacology and Therapeutics
Australian Venom Research Unit Dr David Williams
Pharmacology and Therapeutics
Autologous stem cell therapies in Australia Associate Professor Megan Munsie Anatomy and Neuroscience
Autophagy: a Novel Pathway of Antigen Presentation in Dendritic Cells Professor Jose Villadangos Microbiology and Immunology
Biolpolymer-based vaccine delivery systems Professor David Jackson Microbiology and Immunology
Bo&MeRanG Research Projects Dr Marie Greyer
Can drug-like mimetics of BDNF promote remyelination after injury? Dr Junhua Xiao Anatomy and Neuroscience
Cell biology of membrane receptors regulating the serum half-life of therapeutic proteins Professor Paul Gleeson Biochemistry and Molecular Biology
Contemplating stem cells in society Dr Claire Tanner Anatomy and Neuroscience
Crack laboratory: Neuropharmacology Associate Professor Peter Crack
Pharmacology and Therapeutics
Designing better drugs Dr David Ascher Biochemistry and Molecular Biology
Developing new therapies for Systemic Lupus Erythematosus Professor Fabienne Mackay Microbiology and Immunology
Development of a self-adjuvanting vaccine for enterotoxigenic Escherichia coli (ETEC) Professor David Jackson Microbiology and Immunology
Development of antimalarial drugs Professor Leann Tilley Biochemistry and Molecular Biology
Drug target identification in the malaria parasite Professor Malcolm McConville Biochemistry and Molecular Biology
Drugs targeting digestive disorders, discovery and proof of principle Professor John B Furness Anatomy and Neuroscience
Endothelin pharmacology in the setting of pulmonary hypertension Professor James Angus Pharmacology and Therapeutics Research
Function of MARCH ubiquitin ligases Professor Jose Villadangos Microbiology and Immunology
Furness laboratory: Digestive physiology and nutrition Professor John Furness
Anatomy and Neuroscience
Gleeson laboratory: Membrane trafficking and protein sorting in health and disease and development of new therapeutics Professor Paul Gleeson
Biochemistry and Molecular Biology
Gooley laboratory: Structural biology of disease Associate Professor Paul Gooley
Biochemistry and Molecular Biology
Growth factors and peptide mimetics Dr Susan Northfield Pharmacology and Therapeutics
Gut health in production animals and in human Professor John B Furness Anatomy and Neuroscience
Harnessing dendritic cells for vaccine development Professor Jose Villadangos Microbiology and Immunology
How BDNF signalling controls myelination? Dr Simon Murray Anatomy and Neuroscience
Hughes laboratory: Drug design Associate Professor Tony Hughes
Pharmacology and Therapeutics
Identifying key metabolic pathways required for Toxoplasma gondii infection Professor Malcolm McConville Biochemistry and Molecular Biology
Immuno-paralysis following severe infections or trauma Professor Jose Villadangos Microbiology and Immunology
Innovative approaches to prepare synthetic, partially synthetic and natural product-based vaccines Professor David Jackson Microbiology and Immunology
Ivanusic laboratory: Pain and sensory mechanisms Dr Jason Ivanusic
Anatomy and Neuroscience
Jackson laboratory: Synthetic vaccine design Professor David Jackson
Microbiology and Immunology
Joining the immunotherapy revolution: Adoptive cell therapy against cancer Professor Jose Villadangos Microbiology and Immunology
Lew laboratory: Theoretical and empirical pharmacology Dr Michael Lew
Pharmacology and Therapeutics
Lipopeptide-based adjuvanting systems Professor David Jackson Microbiology and Immunology
McConville laboratory: Molecular microbiology Professor Malcolm McConville
Biochemistry and Molecular Biology
Mechanisms of growth factor signalling Dr Simon Murray Anatomy and Neuroscience
Molecular mechanisms that contribute to bone marrow pain Dr Jason Ivanusic Anatomy and Neuroscience
Munsie laboratory: Ethical, legal and social implications of stem cell research Associate Professor Megan Munsie
Anatomy and Neuroscience
Murray & Xiao laboratory: Neurotrophin and myelin Dr Simon Murray & Dr Junhua Xiao
Anatomy and Neuroscience
Pain management using ultrasound-guided local anaesthetic techniques Dr Jason Ivanusic Anatomy and Neuroscience Research
Patient voices: An analysis of patients’ information-based priorities and needs Associate Professor Megan Munsie Anatomy and Neuroscience
Personalising treatments for genetic diseases Dr David Ascher Biochemistry and Molecular Biology
Preclinical pharmacology – cardiovascular efficacy and safety R&D Associate Professor Christine Wright Pharmacology and Therapeutics
Protein engineering Dr David Ascher Biochemistry and Molecular Biology
Ralph laboratory: Drug targets and gene regulation in Plasmodium falciparum Dr Stuart Ralph
Biochemistry and Molecular Biology
Regulators of plasticity and treatment response in colorectal cancer Associate Professor Frederic Hollande Pathology
Relaxin family peptide hormones Associate Professor Tony Hughes Pharmacology and Therapeutics
Restoring immunocompetency in Chronic Lymphocytic Leukemia Professor Fabienne Mackay Microbiology and Immunology
Tackling drug resistance Dr David Ascher Biochemistry and Molecular Biology
The Cardiovascular Pharmacology of Snake Venoms From Papua New Guinea and Australia Associate Professor Christine Wright Pharmacology and Therapeutics
The gut hormone, ghrelin, its pharmacology, and the possible application of ghrelin receptor agonists in therapy Professor John B Furness Anatomy and Neuroscience
The influence of neurotrophin signalling upon the generation of myelin Dr Simon Murray Anatomy and Neuroscience
The link between cardiovascular disease and neurodegeneration – focus on Alzheimer’s disease Associate Professor Christine Wright Pharmacology and Therapeutics
The Role of CXCR7 in Tissue Fibrosis Dr Asolina Braun Microbiology and Immunology
The role of glucose metabolism and O-GlcNAc glycosylation in the regulation of immunity Dr Nishma Gupta | Professor Jose Villadangos Microbiology and Immunology
The roles of gastrointestinal hormones Professor John B Furness Anatomy and Neuroscience
The Treatment of Papuan Taipan Envenoming in Papua New Guinea Dr David Williams Pharmacology and Therapeutics
Therapeutics & Translation
Trovafloxacin – an antibiotic with additional properties Professor James Angus Pharmacology and Therapeutics
Understanding the molecular basis of myelin repair Dr Junhua Xiao Anatomy and Neuroscience
Understanding the molecular consequences of mutations Dr David Ascher Biochemistry and Molecular Biology
Vagal nerve stimulation for the treatment of inflammatory bowel disease Professor John B Furness Anatomy and Neuroscience
Viral tracing to identify central projections and pathways for sensory neurons that innervate bone Dr Jason Ivanusic Anatomy and Neuroscience
Wolbachia to stop dengue transmission in Vietnam and Indonesia Professor Cameron Simmons Microbiology and Immunology
Wright laboratory: Cardiovascular Therapeutics Unit Associate Professor Christine E Wright
Pharmacology and Therapeutics