Molecular Mechanisms of Disease

A key focus of research within the School is to understand human disease at the molecular level. The modelling of human diseases in experimental systems and analysis of cells and tissues provides insights into the underlying fundamental mechanisms of a range of diseases affecting the nervous system, respiratory system, muscle diseases and infectious disease.

Groups / Projects Research Lead Dept / Centre
A mass spectrometry assay for quantitative analysis of P. falciparum Histidine Rich Protein 2 Professor Gavin E. Reid Biochemistry and Molecular Biology
A universal vaccine against influenza A Professor David Jackson Microbiology and Immunology
Acquisition, Epigenetic and Transcriptional Regulation of CTL Gene Expression Within Both Effector and Memory CTL Professor Stephen Turner Microbiology and Immunology
Alternative splicing in human parasites Dr Stuart Ralph Biochemistry and Molecular Biology
Alzheimer's disease Professor Roberto Cappai Pathology
Analysing genetic roles of translational repressors in Drosophila stem cells Associate Professor Gary Hime Anatomy and Neuroscience
Analysing protein structures Dr David Ascher Biochemistry and Molecular Biology
Analysing the role of a novel zinc finger protein in stem cell maintanence Associate Professor Gary Hime Anatomy and Neuroscience
Analysing the role of transcriptional repressors in Drosophila and mouse stem cells Associate Professor Gary Hime Anatomy and Neuroscience
Analysis of Factors That Determine Immunodominance Hiearchies Professor Stephen Turner Microbiology and Immunology
Angiotensin and chemoreceptor function Professor Andrew Allen Physiology
Antibody dependent cellular cytotoxicity - a neglected anti-HIV iImmune response! Professor Stephen Kent Microbiology and Immunology
Antimicrobial resistant bacterial pathogens Professor Ben Howden Microbiology and Immunology
Apolipoproteins and amyloid fibril formation in disease Dr Michael Griffin Biochemistry and Molecular Biology
Application of genomics to public health and clinical microbiology Professor Ben Howden Microbiology and Immunology
Ascher laboratory: Structural biology and bioinformatics Dr David Ascher
Biochemistry and Molecular Biology
Autophagy and Norovirus replication Associate Professor Jason Mackenzie Microbiology and Immunology
Barrett laboratory: Neural plasticity and neurotrophins Associate Professor Graham Barrett
Physiology
Bedoui laboratory: Innate and adaptive interactions in immunity to infection Associate Professor Sammy Bedoui
Microbiology and Immunology
Biochemical and structural basis of the tumour suppression mechanism of CSK-homologous kinase Associate Professor Heung-Chin Cheng Biochemistry and Molecular Biology
Biolpolymer-based vaccine delivery systems Professor David Jackson Microbiology and Immunology
Bogoyevitch laboratory: Regulatory biology Associate Professor Marie Bogoyevitch
Biochemistry and Molecular Biology
Bornstein laboratory: Enteric neuroscience Professor Joel C Bornstein
Physiology
Brooks laboratory: Innate immunity; anti-viral immunity Professor Andrew Brooks
Microbiology and Immunology
Brown laboratory: Immunology; virology; vaccinology Professor Lorena (Lori) Brown
Microbiology and Immunology
Buchanan laboratory: Oncogenomics (colorectal cancer) Dr Daniel Buchanan
Pathology
Calbindins - what do they do? Professor Mike Hubbard Pharmacology and Therapeutics
Can drug-like mimetics of BDNF promote remyelination after injury? Dr Junhua Xiao Anatomy and Neuroscience
Cappai laboratory: Alzheimer's disease, prion disease, Parkinson's disease and Traumatic Brain Injury Professor Roberto Cappai
Pathology
Carbone laboratory: Immune response to herpes simplex virus Professor Francis (Frank) Carbone
Microbiology and Immunology
Cell surface receptors for attachment and entry of influenza virus into cells of the innate immune system Associate Professor Patrick Reading Microbiology and Immunology
Cell/cell and cell/matrix adhesion in the regulation of tumour-initiating cells Associate Professor Frederic Hollande Pathology
Chalky teeth - can they be prevented? Professor Mike Hubbard Pharmacology and Therapeutics
Characterizing allosteric sites and conformational diversity of G-protein coupled receptors Associate Professor Paul Gooley Biochemistry and Molecular Biology
Checkmating HIV - trapping immune escape HIV strains Professor Stephen Kent Microbiology and Immunology
Cheng laboratory: Molecular enzymology of protein kinases and phosphatases involved in human diseases Associate Professor Heung-Chin Cheng
Biochemistry and Molecular Biology
Chronic immune activation during treated HIV disease Professor Damian Purcell Microbiology and Immunology
Combined influenza-AIDS vaccines Professor Stephen Kent Microbiology and Immunology
Comprehensive lipidome profiling to identify functional biomarkers of colorectal cancer metastasis Professor Gavin E. Reid Biochemistry and Molecular Biology
Correlates of severe and fatal influenza disease in high-risk groups Associate Professor Katherine Kedzierska Microbiology and Immunology
Coulson laboratory: Rotavirus pathogenesis and immunity Associate Professor Barbara Coulson
Microbiology and Immunology
Crack laboratory: Neuropharmcology Associate Professor Peter Crack
Pharmacology and Therapeutics
Crouch laboratory: Neurodegenerative disease Dr Peter Crouch
Pathology
DC targetting vaccines Professor Stephen Kent Microbiology and Immunology
De Iongh laboratory: Ocular development laboratory A/Prof Robb de Iongh
Anatomy and Neuroscience
Deciphering the relative contributions of different dendritic cells to killer T cell responses Associate Professor Sammy Bedoui Microbiology and Immunology
Delbridge laboratory: Cardiac phenomics Professor Lea Delbridge
Physiology
Delineating how CD4 T cells ‘help’ establishing effective killer T cell responses Associate Professor Sammy Bedoui Microbiology and Immunology
Dendritic cell maturation following different microbial stimulation Professor William (Bill) Heath Microbiology and Immunology
Design, development and testing of HIV vaccines Professor Damian Purcell Microbiology and Immunology
Detecting and mapping different protein conformations in live cells Associate Professor Danny Hatters Biochemistry and Molecular Biology
Developing new therapies for Systemic Lupus Erythematosus Professor Fabienne Mackay Microbiology and Immunology
Development of a self-adjuvanting vaccine for enterotoxigenic Escherichia coli (ETEC) Professor David Jackson Microbiology and Immunology
Development of autonomic and nociceptive circuits Professor Janet Keast Anatomy and Neuroscience
Development of new types of antimicrobial agents Professor Roy Robins-Browne Microbiology and Immunology
Diabetic cardiomyopathy – an epidemic disease Professor Lea Delbridge Physiology
Discovering and characterizing new genes involved in innate immunity, tissue injury and fibrosis Professor Christine Wells Anatomy and Neuroscience
Discovery of polyQ ataxin-1 regulation and regulators Associate Professor Marie Bogoyevitch Biochemistry and Molecular Biology
Drug target identification in the malaria parasite Professor Malcolm McConville Biochemistry and Molecular Biology
Enamel cell biology – how is bulk calcium handled safely? Professor Mike Hubbard Pharmacology and Therapeutics
Enterococcus faecium Professor Ben Howden Microbiology and Immunology
ERp29 – what does it do? Professor Mike Hubbard Pharmacology and Therapeutics
Factors that accelerate photoreceptor death: The role of purines Professor Erica Fletcher Anatomy and Neuroscience
Fast foods: Harmful effects of food products on the intestine and liver – AGEs and RAGEs Dr Leni Rivera Anatomy and Neuroscience
Fletcher laboratory: Visual neuroscience Professor Erica Fletcher
Anatomy and Neuroscience
Furness laboratory: Digestive physiology and nutrition Professor John Furness
Anatomy and Neuroscience
Gametocytogenesis - the sexy side of malaria Professor Leann Tilley Biochemistry and Molecular Biology
Gebhardt laboratory: Adaptive immune responses to virus infections Associate Professor Thomas Gebhardt
Microbiology and Immunology
Gene regulation in Plasmodium falciparum Dr Stuart Ralph Biochemistry and Molecular Biology
Gleeson laboratory: Membrane trafficking and protein sorting in health and disease and development of new therapeutics Professor Paul Gleeson
Biochemistry and Molecular Biology
Glial cells as a source of progenitor cells in degenerative disease Professor Erica Fletcher Anatomy and Neuroscience
Glycobiology of bacterial-host interactions Dr Nichollas Scott Microbiology and Immunology
Going places: Intracellular trafficking for effective immunity Dr Justine Mintern Biochemistry and Molecular Biology
Gooley laboratory: Structural biology of disease Associate Professor Paul Gooley
Biochemistry and Molecular Biology
Griffin laboratory: Functional and mis-functional protein-protein interactions Dr Michael Griffin
Biochemistry and Molecular Biology
Gunnersen laboratory: Neuron development and plasticity Dr Jenny Gunnersen
Anatomy and Neuroscience
Hargreaves laboratory: Exercise physiology Professor Mark Hargreaves
Physiology
Hartland laboratory: Molecular basis of host-pathogen interactions Professor Elizabeth Hartland
Microbiology and Immunology
Hatters laboratory: Protein misfolding and proteostasis in neurodegenerative diseases Associate Professor Danny Hatters
Biochemistry and Molecular Biology
Heat Shock Protein therapy for muscle wasting Professor Gordon Lynch Physiology
Heath laboratory: CD8 T lymphocytes, dendritic cells, self tolerance and immunity Professor William (Bill) Heath
Microbiology and Immunology
Hime laboratory: Stem cell genetics Associate Professor Gary Hime
Anatomy and Neuroscience
Hollande laboratory: Molecular mechanisms of tumour progression Associate Professor Fred Hollande
Pathology
How BDNF signalling controls myelination? Dr Simon Murray Anatomy and Neuroscience
How does GM-CSF prevent brain damage after traumatic injury? Dr Jenny Gunnersen
Dr Sandy Shultz
Anatomy and Neuroscience
How does inflammation affect the activity of primary afferent neurons that innervate bone? Dr Jason Ivanusic Anatomy and Neuroscience
How does regulation of nuclear importation affect stem cell maintenance Associate Professor Gary Hime Anatomy and Neuroscience
How does Relaxin activate its G-protein coupled receptor? Associate Professor Paul Gooley Biochemistry and Molecular Biology
How is the immunological T cell memory generated? Associate Professor Katherine Kedzierska Microbiology and Immunology
How sensory signals are detected: Structure function relationships in peripheral sensory nerve terminals Dr Jason Ivanusic Anatomy and Neuroscience
Howden laboratory: Molecular epidemiology, genomics and pathogenesis of antimicrobial resistant bacteria Professor Ben Howden
Microbiology and Immunology
Hoyer laboratory: Translational neuroscience Professor Daniel Hoyer
Pharmacology and Therapeutics
Hubbard & Mangum laboratory: Proteomics and calcium biology Professor Mike Hubbard
Pharmacology and Therapeutics
Hypothalamic modulation of basal sympathetic activity Professor Andrew Allen Physiology
Identification of novel metabolic pathways in Leishmania parasites Professor Malcolm McConville Biochemistry and Molecular Biology
Identifying and characterising Lynch syndrome within the population Dr Daniel Buchanan Pathology
Identifying biomarkers of risk and poor prognosis in CRC Dr Daniel Buchanan Pathology
Identifying key metabolic pathways required for Toxoplasma gondii infection Professor Malcolm McConville Biochemistry and Molecular Biology
Identifying novel genetic risk factors for colorectal cancer Dr Daniel Buchanan Pathology
Imaging effector and memory T cell responses in the skin following Herpes Simplex Virus-1 infection Professor William (Bill) Heath Microbiology and Immunology
Imaging the priming of CD8 Killer T cell responses to Herpes Simplex Virus-1 skin infection Professor William (Bill) Heath Microbiology and Immunology
Immune responses in Legionnaire’s disease Professor Elizabeth Hartland Microbiology and Immunology
Improved vaccines by targeting to dendritic cells Professor William (Bill) Heath Microbiology and Immunology
Improving recovery of injured visceral nerves and their spinal control centres Professor Janet Keast Anatomy and Neuroscience
Improving vaccines: Mechanisms of vaccine biology Dr Justine Mintern Biochemistry and Molecular Biology
Influenza A virus PB1-F2 Protein: a putative virulence factor and initiator of inflammation Dr Julie McAuley Microbiology and Immunology
Influenza–specific ADCC: Role in a universal flu vaccine? Professor Stephen Kent Microbiology and Immunology
Innate immunity and neural injury Associate Professor Peter Crack Pharmacology and Therapeutics
Innate T cell recognition and development Dr Daniel Pellicci Microbiology and Immunology
Innovative approaches to prepare synthetic, partially synthetic and natural product-based vaccines Professor David Jackson Microbiology and Immunology
Interplay of sex differentiation and metabolism Associate Professor Dagmar Wilhelm Anatomy and Neuroscience
Intraepithelial T cells in anti-viral immunity Professor Francis (Frank) Carbone Microbiology and Immunology
Intravital imaging of T cell responses in the brain during cerebral malaria infection Professor William (Bill) Heath Microbiology and Immunology
Investigation of HSV latency and reactivation Professor Francis (Frank) Carbone Microbiology and Immunology
Is the “shed” form of Sez-6 proteins responsible for their synapse-promoting effects? Dr Jenny Gunnersen
Dr Kathryn Munro
Anatomy and Neuroscience
Isolation and Characterization of Major Venom Proteins From Scyphozoan Jellyfish Associate Professor Christine Wright Pharmacology and Therapeutics
Ivanusic laboratory: Pain and sensory mechanisms Dr Jason Ivanusic
Anatomy and Neuroscience
Jackson laboratory: Synthetic vaccine design Professor David Jackson
Microbiology and Immunology
Keast & Osborne laboratory: Neural development, injury and pain Professor Janet Keast & Dr Peregrine Osborne
Anatomy and Neuroscience
Kedzierska laboratory: Immunity to pandemic and newly emerged influenza viruses Associate Professor Katherine Kedzierska
Microbiology and Immunology
Kent laboratory: HIV vaccines; immune responses to HIV-1; immunotherapy Professor Stephen Kent
Microbiology and Immunology
Kilpatrick laboratory: Neuroimmunology of Multiple Sclerosis Professor Trevor Kilpatrick
Anatomy and Neuroscience
Klebsiella pneumoniae Professor Dick Strugnell Microbiology and Immunology
Koopman laboratory: Clinical nutrition and muscle metabolism Dr René Koopman
Physiology
Lawson laboratory: Neurodegenerative disease caused by prions Associate Professor Vicki Lawson
Pathology
Lipidome profiling of inflammatory biomarkers for beta cell autoimmunity in type 1 diabetes Professor Gavin E. Reid Biochemistry and Molecular Biology
Lipopeptide-based adjuvanting systems Professor David Jackson Microbiology and Immunology
Lung disease Professor Gary Anderson
Pharmacology and Therapeutics
Lynch laboratory: Basic and clinical myology Professor Gordon Lynch
Physiology
Mackay (F) laboratory: B lymphocytes, BAFF, autoimmunity and cancer Professor Fabienne Mackay
Microbiology and Immunology
Mackay (L) laboratory: Tissue-resident memory T cells; lymphocyte differentiation; peripheral immunity Dr Laura Mackay
Microbiology and Immunology
Mackenzie laboratory: Intracellular virus replication and innate immunity Associate Professor Jason Mackenzie
Microbiology and Immunology
Malaria and Tissue Resident Memory T cells (TRM) in the liver Professor William (Bill) Heath Microbiology and Immunology
Mapping the distribution of angiotensin receptors in the brain Professor Andrew Allen Physiology
Mature and developing synaptic transmission between defined classes of enteric neurons Dr Jaime Foong
Physiology
McCluskey laboratory: Role of MAIT cells in health and disease Professor James McCluskey
Microbiology and Immunology
McConville laboratory: Molecular microbiology Professor Malcolm McConville
Biochemistry and Molecular Biology
Mechanisms of growth factor signalling Dr Simon Murray Anatomy and Neuroscience
Mechanisms underlying early generation of human T cell memory Associate Professor Katherine Kedzierska Microbiology and Immunology
Memory T cell responses in the lung during virus infection Dr Linda Wakim Microbiology and Immunology
Mintern laboratory: Vaccine biology Dr Justine Mintern
Biochemistry and Molecular Biology
Mitochondrial protein biogenesis in mammalian cells Dr Diana Stojanovski Biochemistry and Molecular Biology
Molecular and cellular analysis of mammalian ovary development and disease Associate Professor Dagmar Wilhelm Anatomy and Neuroscience
Molecular immunology and autoimmunity Professor Paul Gleeson Biochemistry and Molecular Biology
Molecular Mechanisms of Disease
Mucosal immune responses during bacterial diarrhoea Dr Catherine Kennedy Microbiology and Immunology
Mueller laboratory: Adaptive immune responses to infection, lymphoid stromal cells, and imaging the immune system Associate Professor Scott Mueller
Microbiology and Immunology
Murray & Xiao laboratory: Neurotrophin and myelin Dr Simon Murray & Dr Junhua Xiao
Anatomy and Neuroscience
Mycobacterium ulcerans Professor TIm Stinear Microbiology and Immunology
Nanoparticle HIV vaccines Professor Stephen Kent Microbiology and Immunology
Nanoparticle Modulation of Mast Cell Function Dr Graham Mackay
Pharmacology and Therapeutics
Newton laboratory: Virulence strategies of intracellular bacterial pathogens Dr Hayley Newton
Microbiology and Immunology
NK cell receptor biology Professor Andrew Brooks Microbiology and Immunology
NKT cells, MAIT cells and HIV Professor Stephen Kent Microbiology and Immunology
Non-classical MHC and Class 1-like molecules Professor Andrew Brooks Microbiology and Immunology
Norovirus replication and innate immunity Associate Professor Jason Mackenzie Microbiology and Immunology
Novel drugs and receptors for targeting digestive function Dr Leni Rivera Anatomy and Neuroscience
Novel Mast Cell-Derived Mediators Dr Graham Mackay Pharmacology and Therapeutics
Nutrition: How micronutrients modify digestive function Dr Brid Callaghan Anatomy and Neuroscience
Oxidative stress and neural injury Associate Professor Peter Crack Pharmacology and Therapeutics
Parkinson's disease Professor Roberto Cappai Pathology
Passive antibody immunity for use in combination microbicides Professor Damian Purcell Microbiology and Immunology
Pathogenic bacteria that target mitochondria Dr Diana Stojanovski Biochemistry and Molecular Biology
Personalising treatments for genetic diseases Dr David Ascher Biochemistry and Molecular Biology
Pharmacological interventions to attenuate muscle wasting in cancer cachexia Professor Gordon Lynch Physiology
Post-translational control of cell fate decisions Associate Professor Dagmar Wilhelm Anatomy and Neuroscience
Potential of cell therapy to treat Hirschsprung’s disease Professor Heather Young
Dr Lincon Stamp
Anatomy and Neuroscience
Probing microtubule organisation Associate Professor Marie Bogoyevitch Biochemistry and Molecular Biology
Proliferation of enteric neuron precursors Professor Heather Young
Professor Heather Young
Anatomy and Neuroscience
Protein kinases involved in pathogenesis of Parkinson’s disease Associate Professor Heung-Chin Cheng Biochemistry and Molecular Biology
Purcell laboratory: Viral RNA elements, regulation of HIV replication, HIV antibody vaccine Professor Damian Purcell
Microbiology and Immunology
Ralph laboratory: Drug targets and gene regulation in Plasmodium falciparum Dr Stuart Ralph
Biochemistry and Molecular Biology
Reading laboratory: Innate immune detection and response to respiratory virus infections Associate Professor Patrick Reading
Microbiology and Immunology
Regulation of Mast Cell Activation Dr Graham Mackay Pharmacology and Therapeutics
Regulation of Tissue-Resident Memory T cell development Dr Laura Mackay Microbiology and Immunology
Regulators of plasticity and treatment response in colorectal cancer Associate Professor Frederic Hollande Pathology
Reid laboratory: Proteomics and lipidomics in health and disease Professor Gavin E. Reid
Biochemistry and Molecular Biology
Restoring immunocompetency in Chronic Lymphocytic Leukemia Professor Fabienne Mackay Microbiology and Immunology
RNA mediated control of HIV-1 gene expression Professor Damian Purcell Microbiology and Immunology
Robins-Browne laboratory: Medical bacteriology, pathogenesis, bacterial genetics, therapeutics Professor Roy Robins-Browne
Microbiology and Immunology
Role of cellular lipids during Flavivirus replication Associate Professor Jason Mackenzie Microbiology and Immunology
Role of innate signals in inducing protective T cell immunity Associate Professor Sammy Bedoui Microbiology and Immunology
Role of Sez-6 in cocaine self‐administration and extinction Dr Jenny Gunnersen
Professor Andrew Lawrence
Anatomy and Neuroscience
Role of SOCS3 in defective muscle repair during ageing Professor Gordon Lynch Physiology
Rotavirus induction and evasion of innate immunity Associate Professor Barbara Coulson Microbiology and Immunology
Rotavirus modulation of type 1 diabetes development Associate Professor Barbara Coulson Microbiology and Immunology
Rotavirus-cell binding and entry Associate Professor Barbara Coulson Microbiology and Immunology
Salmonella Typhimurium Professor Dick Strugnell Microbiology and Immunology
Saunders laboratory: Developmental neuroscience and neurotrauma Professor Norman Saunders
Pharmacology and Therapeutics
Self-tolerance: Interactions between thymic stroma and dendritic cells Professor William (Bill) Heath Microbiology and Immunology
Signals for endosomal sorting in development and disease Professor Paul Gleeson Biochemistry and Molecular Biology
Simmons laboratory: Dengue; pathogenesis, epidemiology, therapeutics, entomology Professor Cam Simmons
Microbiology and Immunology
Soluble barriers to influenza virus infection Associate Professor Patrick Reading Microbiology and Immunology
Southey laboratory: Genetic epidemiology laboratory Professor Melissa Southey
Pathology
Spinal cord injury: Failure of bowel control Dr Brid Callaghan Anatomy and Neuroscience
Staphylococcus aureus & Enterococcus faecium Professor Tim Stinear Microbiology and Immunology
Staphylococcus aureus and Staphylococcus epidermidis Professor Ben Howden Microbiology and Immunology
Steroid hormones and heart failure – sex perspectives Professor Lea Delbridge Physiology
Stojanovski laboratory: Mitochondrial biogenesis in health and disease Dr Diana Stojanovski
Biochemistry and Molecular Biology
Stress granules Associate Professor Danny Hatters Biochemistry and Molecular Biology
Stroke Associate Professor Peter Crack Pharmacology and Therapeutics
Structural Determinants of CTL TCR Diversity and PMHC Recognition Professor Stephen Turner Microbiology and Immunology
Strugnell laboratory: Bacterial pathogenesis and host responses Professor Dick Strugnell
Microbiology and Immunology
T cell immunity in the periphery Dr Laura Mackay Microbiology and Immunology
T cells in peripheral immunity Professor Francis (Frank) Carbone Microbiology and Immunology
Tackling drug resistance Dr David Ascher Biochemistry and Molecular Biology
The Enteric Neural Circuitry Activated During Bacterial-toxin Induced Diarrhoea Dr Jaime Foong Physiology
The GDNF family, peripheral nerve regeneration and pain Professor Janet Keast Anatomy and Neuroscience
The influence of neurotrophin signalling upon the generation of myelin Dr Simon Murray Anatomy and Neuroscience
The innate immune system in the respiratory tract Professor David Jackson Microbiology and Immunology
The link between cardiovascular disease and neurodegeneration – focus on Alzheimer's and Parkinson's diseases Associate Professor Christine Wright Pharmacology and Therapeutics
The mechanisms of viral escape in murine and human influenza infection Associate Professor Katherine Kedzierska Microbiology and Immunology
The molecular basis of the propagation of molecular strain types of prions Associate Professor Vicki Lawson Pathology
The role of CD4+ T cells in viral infections Professor Andrew Brooks Microbiology and Immunology
The role of Egr genes in retinal remodelling A/Prof Robb de Iongh
Anatomy and Neuroscience
The Role of enteric neurons in gastrointestinal symptoms associated with Autism Spectrum disorders Dr Elisa Hill-Yardin Physiology
The role of glia in inner retinal changes during retinal degeneration Professor Erica Fletcher Anatomy and Neuroscience
The role of glial cells in retinal vascular disease Professor Erica Fletcher Anatomy and Neuroscience
The role of glycosaminoglycan in the propagation of prions Associate Professor Vicki Lawson Pathology
The role of Hedgehog signalling during ocular morphogenesis A/Prof Robb de Iongh
Anatomy and Neuroscience
The role of innate immune cells in protection and pathology during influenza virus infection Associate Professor Patrick Reading Microbiology and Immunology
The role of microglia in age-related macular degeneration Professor Erica Fletcher Anatomy and Neuroscience
The role of non-coding RNA in embryonic development Associate Professor Dagmar Wilhelm Anatomy and Neuroscience
The role of the rabies P protein in evading the interferon-mediated pathway Associate Professor Paul Gooley Biochemistry and Molecular Biology
The structure of the IL-11 signalling complex Dr Michael Griffin Biochemistry and Molecular Biology
The unique features of visceral pain Professor Janet Keast Anatomy and Neuroscience
Therapeutic potential of Heat Shock Protein 72 induction in muscular dystrophy Professor Gordon Lynch Physiology
Tracking phenotypically and functionally distinct T cell subsets via T cell repertoire diversity Associate Professor Katherine Kedzierska Microbiology and Immunology
Tracking the aggregation knetics of mutant proteins in cells Associate Professor Danny Hatters Biochemistry and Molecular Biology
Transgenic approach to reprogramming retinal glia to stem/progenitor cells A/Prof Robb de Iongh
Anatomy and Neuroscience
Translocated Dot/Icm effectors of Legionella Dr Shivani Pasricha Microbiology and Immunology
Translocated Type III secretion system effectors of bacterial pathogens Dr Jaclyn Pearson Microbiology and Immunology
Traumatic brain injury Associate Professor Peter Crack Pharmacology and Therapeutics
Uncovering the interplay between innate immunity and the blood brain barrier in disorders of the CNS Professor Christine Wells Anatomy and Neuroscience
Understanding neuro-urothelial communication Professor Janet Keast Anatomy and Neuroscience
Understanding the aetiology of hypertension Professor Andrew Allen Physiology
Understanding the aetiology of Serrated Polyposis Syndrome Dr Daniel Buchanan Pathology
Understanding the cellular cues that direct muscle stem cell specification Professor Gordon Lynch Physiology
Understanding the interaction between microbiota and T cell immunity Associate Professor Sammy Bedoui Microbiology and Immunology
Understanding the molecular basis of myelin repair Dr Junhua Xiao Anatomy and Neuroscience
Understanding the molecular consequences of mutations Dr David Ascher Biochemistry and Molecular Biology
Understanding the role of angiotensin in the rostral ventrolateral medulla Professor Andrew Allen Physiology
Understanding the role of glycine in the control of skeletal muscle mass during sepsis Dr René Koopman Physiology
Understanding ‘universal’ influenza-specific CD8+ T cell responses Associate Professor Katherine Kedzierska Microbiology and Immunology
Using biochemical approaches to investigating the trafficking and mechanism of action of the antiviral molecule, IFITM3 Dr Linda Wakim Microbiology and Immunology
Vaccination against liver-stage Plasmodium for malaria prevention Professor William (Bill) Heath Microbiology and Immunology
van Driel laboratory: Immune responses to pathogens Professor Ian van Driel
Biochemistry and Molecular Biology
Villadangos laboratory: Antigen presenting cells & molecules that initiate T cell immunity against pathogens and cancer Professor Jose Villadangos
Microbiology and Immunology
Viral interactions with the innate immune system Associate Professor Patrick Reading Microbiology and Immunology
Visualization and formation West Nile Virus replication complexes Associate Professor Jason Mackenzie Microbiology and Immunology
Wakim laboratory: Antiviral molecules, mucosal immunology, influenza virus, tissue resident memory T cells Dr Linda Wakim
Microbiology and Immunology
West Nile Virus replication and cellular stress responses Associate Professor Jason Mackenzie Microbiology and Immunology
What is the function of Sez6L2 in the forebrain? Dr Jenny Gunnersen
Dr Kathryn Munro
Anatomy and Neuroscience
Wilhelm laboratory: Sex determination and disorders of sex development Associate Professor Dagmar Wilhelm
Anatomy and Neuroscience
Young laboratory: Development of the enteric nervous system Prof Heather Young
Anatomy and Neuroscience